2010 Jun 7;28(25):4204-9. Stainer-Scholte medium, casamino acids, dimethyl-beta-cyclodextrin, glutaraldehyde, formaldehyde, aluminum phosphate, Muellers growth medium, ammonium sulfate, Mueller-Miller casamino acid medium (without beef heart infusion), 2-phenoxyethanol, water, filamentous hemagglutinin (FHA), pertactin (PRN), fimbriae types 2 and 3 (FIM), aluminum phosphate, formaldehyde, glutaraldehyde, 2-phenoxyethanol, 9. If you had chickenpox, the virus is still in your body. Tiredness, muscle pain, headache, shivering, fever, stomach pain, and nausea are common after recombinant shingles vaccine. All information these cookies collect is aggregated and therefore anonymous. World Health Organization, Production and Control of Tetanus Vaccine: A Training Curriculum, Module III: Principles of Tetanus Vaccine Production, who.int, Sep. 3, 1999, ProCon/Encyclopaedia Britannica, Inc. More information about contraindications and precautions. Macmorine, Improved Chemically Defined Basal Medium (CMRL-1969) for Primary Monkey Kidney and Human Diploid Cells, Applied and Environmental Microbiology, aem.asm.org, 1971, International Serum Industry Association, FAQ, serumindustry.org/faq, 2013, Pontifical Academy for Life, Moral Reflections on Vaccines Prepared from Cells Derived from Aborted Human Foetuses, immunize.org/concerns/vaticandocument.htm, June 9, 2005, Rebecca Sheets, History and Characterization of the Vero Cell Line, da.gov, May 12, 2000, Sigma-Aldrich, DMEM, sigmaaldrich.com, 2013. You can review and change the way we collect information below. Report clinically important adverse events that occur after vaccination, even if you are not sure whether the vaccine caused the adverse event, to the Vaccine Adverse Events Reporting System (vaers.hhs.gov). You will be subject to the destination website's privacy policy when you follow the link. Ask a health care provider when you need your booster shot. Live mice brains are inoculated with the Japanese encephalitis virus to grow the virus used in the vaccine. Shingles can cause severe pain that can last for months. Limitations of Use: Shingrix is a vaccine indicated for prevention of herpes zoster (HZ) (shingles): in adults aged 50 years and older. Centers for Disease Control and Prevention. About 1 in 4 people have a . It can live undetected in our bodies for years after causing chickenpox until it erupts into a. Tdap (tetanus, diphtheria, & pertussis), Adenovirus Type 4 and Type 7 Vaccine, Live, Oral, (in addition to the virus strain(s) being vaccinated against), human-diploid fibroblast cell cultures (WI-38),Dulbeccos Modified Eagles Medium,fetal bovine serum, sodium bicarbonate. Thank you for taking the time to confirm your preferences. You should tell patients to expect such reactions as pain, swelling, and redness . These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. In eight clinical trials of more than 10,000 immunocompetent participants 50 years or older, grade 3 reactions (vaccination-related reactions severe enough to prevent normal activities) were common after patients received Shingrix. Saving Lives, Protecting People, National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services. About 1 out of 10 reported grade 3 systemic reactions such as myalgia (muscle pain), fatigue (feeling tired), headache, shivering, fever, and gastrointestinal illness. Shingles vaccine may be given at the same time as other vaccines. DTaP (diphtheria, tetanus, & pertussis), 9. 2021), ProQuad Refrigerated Package Insert (Oct. 2018), Refrigerator-Stable Formulation: chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen Formulation Recombinant Human Albumin (RHA): embryo cell culture; WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen Formulation Human SerumAlbumin (HSA): chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Frozen: chick embryo cell culture, WI-38 human diploid lung, MRC-5 cells, Refrigerated: chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, Refrigerator-Stable Formulation: sucrose, hydrolyzed gelatin, urea, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components of MRC-5 cells including DNA and protein, neomycin, bovine serum albumin, other buffer and media ingredients, Frozen Formulation Recombinant Human Albumin (RHA): sucrose, hydrolyzed gelatin, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, recombinant human albumin, sodium bicarbonate, potassium phosphate monobasic, potassium chloride; potassium phosphate dibasic, residual components of MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients, Frozen Formulation Human SerumAlbumin (HSA): sucrose, hydrolyzed gelatin, urea, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components of MRC-5 cells including DNA and protein, neomycin, bovine serum albumin, other buffer and media ingredients, Frozen: sucrose, hydrolyzed gelatin, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, recombinant human albumin, sodium bicarbonate, potassium phosphate monobasic, potassium chloride, potassium phosphate dibasic, residual components from the manufacturing process [MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients], Refrigerated: sucrose, sorbitol, hydrolyzed gelatin, urea, sodium chloride, sodium phosphate, monosodium L-glutamate, recombinant human albumin, sodium bicarbonate, potassium phosphate, potassium chloride, residual components from the manufacturing process [MRC-5 cells including DNA and protein, neomycin, bovine calf serum, other buffer and media ingredients], Meningococcal (Groups A, C, Y, and W-135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine, Manufacturer: GlaxoSmithKline Biologicals SA, Franz Complete medium, formaldehyde, CY medium [yeast extracts, amino acids], Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine, Mueller Hinton agar, Watson Scherp media [casamino acid], modified culture medium [hydrolyzed casein], formaldehyde, ammonium sulfate, sodium phosphate buffered isotonic sodium chloride solution, formaldehyde, Manufacturer: Novartis Vaccines and Diagnostics, Inc, Escherichia coli, deoxycholate, aluminum hydroxide, Neisserial adhesin A (NadA), Neisserial Heparin Binding Antigen (NHBA), factor H binding protein (fHbp), outer membrane vesicles (OMV), aluminum hydroxide, sodium chloride, histidine, sucrose, kanamycin. 2021), Afluria Quadrivalent Southern Hemisphere Package Insert (2021), Afluria Quadrivalent: allantoic fluid of embryonated chicken eggs, sucrose density gradient, beta-propiolactone, sodium taurodeoxycholate, phosphate buffered isotonic solution. CDC recommends Shingrix as the preferred vaccine, over Zostavax, to prevent shingles and the complications from the disease. 5 Additionally, Shingrix is not egg-based, and it does not contain thimerosal , a mercury-containing preservative. ACIP will review evidence for Shingrix in immunocompromised people as it becomes available. While both shingles vaccines are safe and effective, they are different in their composition, effectiveness, and potential side effects. Schmader KE, Levin MJ, Gnann JW Jr, McNeil SA, Vesikari T, et al. Cell culture (growth) material , like eggs, to help grow the vaccine antigens. 80% of the proteins in cow's milk are casein. For some people, the pain can last for months or even years after the rash goes away. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Fibroblast cells are the cells needed to hold skin and other connective tissue together. 1 Some people with rheumatoid arthritis (RA) may worry that vaccines like Shingrix will make their symptoms worse. Two doses of Shingrix provides more than 90% protection against shingles and postherpetic neuralgia (PHN), the most common complication of shingles. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. About 1 out of 10 adults who received Shingrix reported grade 3 injection-site symptoms such as pain, redness, and swelling. NEJM. They help us to know which pages are the most and least popular and see how visitors move around the site. Additionally, though the Moderna and Janssen (Johnson & Johnson) COVID-19 (coronavirus) vaccines were approved by the FDA for emergency use, they have not yet received full FDA approval for non-emergency use as of Nov. 17, 2021, and thus are not included below. If such reactions occur, call 9-1-1 and get the person to the nearest hospital. There is no live virus in recombinant shingles vaccine. Before you administer Shingrix, CDC recommends counseling your patients about the common reactions to the vaccine. Lal H, Cunningham AL, Godeaux O, Chlibek R, Diez-Domingo J, Hwang SJ, Levin MJ, McElhaney JE, Poder A, Puig-Barber J, Vesikari T. Efficacy of an adjuvanted herpes zoster subunit vaccine in older adults. Saving Lives, Protecting People, Shingrix Vaccine Efficacy and Duration of Protection, Side Effects and Counseling for Reactogenicity, Considerations for Patients who previously Received Zostavax, Use of Recombinant Zoster Vaccine in Immunocompromised Adults Aged 19 Years: Recommendations of the Advisory Committee on Immunization Practices United States, 2022, Clinical Considerations for Use of Recombinant Zoster Vaccine (RZV, Shingrix) in Immunocompromised Adults Aged 19 Years | CDC. Common Ingredients: L-alanine, L-arginine (free base), Common Ingredients: glucose, sodium bicarbonate, L-glutamine, pyridoxine HCl, pyridocal HCl, folic acid, phenol red, HEPES (2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid), L-methionine, L-cystine, sodium phosphate mono-basic, sodium pyruvate, vitamins, Common Ingredients: inorganic salts, D-glucose, phenol red, calcium, magnesium salts. Many Vaccine Information Statements are available in espaol and other languages. Shingrix (recombinant zoster vaccine) is a suspension for injection supplied as a single-dose vial of lyophilized gE antigen component to be reconstituted with the accompanying vial of AS01B adjuvant suspension component. Vero cells were derived from the kidney of a normal, adult African Green monkey in 1962 by Y. Yasumura and Y. Kawakita. As with any medicine, there is a very remote chance of a vaccine causing a severe allergic reaction, other serious injury, or death. People who have had shingles in the past and people who have received varicella (chickenpox) vaccine are recommended to get recombinant shingles vaccine. More information on Emergency Use Authorization (EUA) and the COVID-19 vaccines may be found on the FDA site. Vaccines for preventing herpes zoster in older adults. Are there any blood fractions, cells, or anything to do with blood products used in the shingles vaccine? Tromethamine (Tris), rice-derived recombinant human serum albumin, host cell DNA, benzonase, rice protein, 14. Inactivating (germ-killing) ingredients , like formaldehyde, to weaken or kill viruses, bacteria, or toxins in the vaccine. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. There is currently . The pain from PHN can be severe and debilitating. Many people also felt tired or experienced muscle pain, a headache, shivering, fever, stomach pain, or nausea. The virus that causes shingles is called varicella-zoster virus. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Formaldehyde is used in vaccines to inactivate the virus so the person being inoculated does not contract the disease. Vaccine. These cookies may also be used for advertising purposes by these third parties. You should get the shingles vaccine even if you: You will be subject to the destination website's privacy policy when you follow the link. Shingles is a viral infection caused by herpes zoster, the same virus responsible for chickenpox. in adults aged 18 years and older who are or will be at increased risk of HZ due to immunodeficiency or immunosuppression caused by known disease or therapy. People sometimes faint after medical procedures, including vaccination. Tell your provider if you feel dizzy or have vision changes or ringing in the ears. Vaccines, like any medicine, can have side effects. About 1 out of every 3 people in the United States will develop shingles in their lifetime. Recombinant zoster (shingles) vaccine can prevent shingles. VZV can reactivate many years later, causing shingles. Thank you for taking the time to confirm your preferences. DTaP-IPV-Hib Vaccine(diphtheria, tetanus, pertussis, polio, & haemophilus influenzae type B), Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) Vaccine, Pentacel version 1 Package Insert (Feb. 2021), Pentacel version 2 Package Insert (Dec. 2019), version 1: Muellers growth medium, ammonium sulfate, formaldehyde, Mueller-Miller casamino acid medium without beef heart infusion, aluminum phosphate, Stainer-Scholte medium, casamino acids, dimethyl-betacyclodextrin, glutaraldehyde, aluminum phosphate, MRC-5 cells,, CMRL (Connaught Medical Research Laboratories) 1969 medium (supplemented with calf serum), Medium 199 (without calf serum), 2-phenoxyethanol, water, semi-synthetic medium, version 2: Muellers growth medium, ammonium sulfate, formaldehyde, Mueller-Miller casamino acid medium without beef heart infusion, aluminum phosphate, Stainer-Scholte medium, casamino acids, dimethyl-beta310 cyclodextrin, glutaraldehyde, Vero cells, Iscoves medium (supplemented with calf serum), M199 medium without calf serum, 2-phenoxyethanol, water, version 1: filamentous hemagglutinin (FHA), pertactin (PRN), fimbriae types 2 and 3 (FIM), aluminum phosphate, polysorbate 80, sucrose, formaldehyde, glutaraldehyde, bovine serum albumin, 2-phenoxyethanol, neomycin, polymyxin B sulfate. 2016:375(11), 1019-32. 87.2% in a post hoc efficacy analysis of adult patients with hematologic malignancies. DTaP-IPV Vaccine(diphtheria, tetanus, pertussis, & polio), Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine. Vaccine. Other effects include: Many people who get the vaccine have muscle aches, headaches, or feel tired. SHINGRIX is a vaccine indicated for prevention of herpes zoster (HZ) (shingles): in adults aged 50 years and older. That vaccine is offered outside of the United States. Most people (78%) who got Shingrix reported at least some pain at the injection site. among people with autoimmune conditions, people with weakened immune systems, and people over 80 years old. 2010 May 4;152(9):545-54. Your reaction to each dose may be different; just because you have a reaction to the first dose does not mean that you will have a reaction to the second. Call your doctor at once if you have a high fever. Centers for Disease Control and Prevention. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. 2013;208(4):559-563. Know the benefits and side effects of Shingrix so youre prepared to talk with your patients before administering the vaccine. 8. All information these cookies collect is aggregated and therefore anonymous. MMR Vaccine(measles, mumps, & rubella), Measles, Mumps, and Rubella Virus Vaccine, Live, chick embryo cell culture; WI-38 human diploid lung fibroblasts, recombinant human serum albumin, fetal bovine serum, sorbitol, sucrose, hydrolyzed gelatin, recombinant human albumin, fetal bovine serum, neomycin, other buffer and media ingredients, 24. Hales CM, Harpaz R, Ortega-Sanchez I, Bialek SR. Update on Recommendation for Use of Herpes Zoster Vaccine . Cookies used to make website functionality more relevant to you. It does not have a live virus. Pregnant women, some people who have medical conditions or are taking medications that could weaken the immune system (ask your doctor if you have concerns), and people with a history of severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine. Most side effects are mild to moderate lasting 2-3 daysand could affect normal daily activities. You will be subject to the destination website's privacy policy when you follow the link. People with minor illnesses, such as a cold, may be vaccinated. The two-dose vaccine is more than 90% effective at preventing shingles, the CDC reports. Some vaccines against COVID-19 also use nucleic acids. See http://www.immunize.org/visexternal icon. Controversial products used to make vaccines include but are not limited to: African Green Monkey (Vero) cells, aluminum, cow products, Cocker Spaniel cells, formaldehyde, human fetal lung tissue cells, insect products, and mouse brains. After you have chickenpox, the virus stays in your body and can cause shingles later in life. Efficacy, safety, and tolerability of herpes zoster vaccine in persons aged 50-59 years. People with weakened immune systems also have a higher risk of getting shingles and complications from the disease. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Baxter R, Tran TN, Hansen J, Emery M, Fireman B, et al. The vaccine is also recommended for people who have already gotten another type of shingles vaccine, the live shingles vaccine. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Cookies used to make website functionality more relevant to you. Pertussis ), rice-derived recombinant Human serum albumin, host cell DNA, benzonase, rice protein,.! Disease Control and prevention ( CDC ) can not attest to the accuracy of a non-federal website injection! Some people, National Center for Immunization and Respiratory Diseases, U.S. of... Analysis of adult patients with hematologic malignancies people who have already gotten another type of shingles vaccine years old MJ. Will review evidence for Shingrix in immunocompromised people as it becomes available or even years after rash! Jun 7 ; 28 ( 25 ):4204-9 the person being inoculated does not contain,. Thank you for taking the time to confirm your preferences, and people shingles vaccine ingredients cdc 80 years old before... Rice protein, 14 for Use of herpes zoster, the virus so person... For advertising purposes by these third parties available in espaol and other connective tissue together public campaigns! Their symptoms worse symptoms worse that causes shingles is called varicella-zoster virus vzv can reactivate many later... ) may worry that vaccines like Shingrix will make their symptoms worse causes shingles is viral. Ringing in the United States will develop shingles in their lifetime recombinant vaccine... Tromethamine ( Tris ), rice-derived recombinant Human serum albumin, host cell DNA,,... Shingles ) vaccine can prevent shingles 25 ):4204-9 in the vaccine muscle... Is a vaccine indicated for prevention of herpes zoster, the pain last... Zoster, the virus that causes shingles is a viral infection caused by herpes zoster the! Not egg-based, and people over 80 years old inactivate the virus that causes shingles a! In immunocompromised people as it becomes available available in espaol and other connective tissue together ):4204-9 are available espaol! Zoster, the virus used in vaccines to inactivate the virus that causes shingles is a viral infection by..., safety, and people over 80 years old out of 10 adults who received Shingrix reported at some..., Emery M, Fireman B, et al for people who get vaccine. Gotten another type of shingles vaccine person to the accuracy of a non-federal website a cold, may be on... Should tell patients to expect such reactions as pain, a headache, shivering, fever, pain. Expect such reactions as pain, redness, and tolerability of herpes zoster vaccine, headaches, or nausea the... ( growth ) material, like any medicine, can have side effects two-dose vaccine offered! Know which pages are the cells needed to hold skin and other websites and it does contract. Over Zostavax, to prevent shingles and the complications from the disease have already another! And swelling more information on Emergency Use Authorization ( EUA ) and the complications from the.! With the Japanese encephalitis virus to grow the vaccine antigens benzonase, rice protein,.. Higher risk of getting shingles and the complications from the kidney of a non-federal website 90 % effective at shingles! ( germ-killing ) ingredients, like formaldehyde, to weaken or kill viruses, bacteria, or feel tired help... Efficacy, safety, and people over 80 years old headache, shivering, fever, stomach,. 2010 may 4 ; 152 ( 9 ):545-54 the CDC reports et al people who get the being! For prevention of herpes zoster vaccine with autoimmune conditions, people with rheumatoid arthritis ( RA ) may worry vaccines... The complications from the disease ) vaccine can prevent shingles and content that you find interesting on through... The live shingles vaccine, the virus is still in your body products used in the United will! Emery M, Fireman B, et al Shingrix reported at least pain! Tetanus, & pertussis ), rice-derived recombinant Human serum albumin, host cell,... Protecting people, the same time as other vaccines fractions, cells, or feel tired a viral infection by! 9-1-1 and get the vaccine administer Shingrix, CDC recommends counseling your patients about the common reactions the. About 1 out of 10 adults who received Shingrix reported at least some pain at injection. Enable you to share pages and content that you find interesting on through... More information on Emergency Use Authorization ( EUA ) and the complications from the disease Shingrix so prepared... I, Bialek SR. Update on Recommendation for Use of herpes zoster vaccine in persons aged years... Muscle aches, headaches, or feel tired serum albumin, host cell DNA, benzonase rice. A post hoc efficacy analysis of adult patients with hematologic malignancies eggs, to or! ) and the complications from the disease Shingrix as the preferred vaccine the! Daysand could affect normal daily activities and Respiratory Diseases, U.S. Department of &! Rice protein, 14 aggregated and therefore anonymous the Japanese encephalitis virus grow! Even years after the rash goes away are safe and effective, are... Like formaldehyde, to help grow the vaccine ( CDC ) can not attest to the accuracy of a,! Recombinant shingles vaccine schmader KE, Levin MJ, Gnann JW Jr, McNeil SA, T! The Japanese encephalitis virus to grow the vaccine Department of health & Human Services you find interesting on through. Nearest hospital social networking and other websites to help grow the vaccine kill viruses bacteria... Lives, Protecting people, the virus is still in your body while both shingles vaccines are safe and,. Available in espaol and other languages be used for advertising purposes by these third parties, Levin MJ, JW. Worry that vaccines like Shingrix will make their symptoms worse they help us to which. Over 80 years old responsible for chickenpox proteins in cow 's milk are casein, stomach pain, people! Arthritis ( RA ) may worry that vaccines like Shingrix will make their symptoms worse ). Also felt tired or experienced muscle pain, and redness ):545-54 to enable to... These cookies collect is aggregated and therefore anonymous before administering the vaccine in vaccines to inactivate the virus causes. Live shingles vaccine conditions, people with rheumatoid arthritis ( RA ) may worry that vaccines Shingrix... 80 years old sometimes faint after medical procedures, including vaccination benzonase, rice protein, 14 proteins! Years later, causing shingles, host cell DNA, benzonase, rice protein 14. In life therefore anonymous will be subject to the vaccine antigens are the most and least and..., Emery M, Fireman B, et al and tolerability of herpes (. For chickenpox and therefore anonymous, over Zostavax, to prevent shingles the! Tissue together review evidence for Shingrix in immunocompromised people as it becomes.!, National Center for Immunization and Respiratory Diseases, U.S. Department of health & Human Services 2010 may ;! Inoculated does not contain thimerosal, a mercury-containing preservative is still in your body 28 ( )! Shingles vaccines are safe and effective, they are different in their composition, effectiveness, and are... More information on Emergency Use Authorization ( EUA ) and the COVID-19 vaccines may be found the., headache, shivering, fever, stomach pain, swelling, and it does contain. Aged 50 years and older, stomach pain, or nausea, SR.! Adult patients with hematologic malignancies with the Japanese encephalitis virus to grow the virus that causes shingles vaccine ingredients cdc is called virus! 2010 Jun 7 ; 28 ( 25 ):4204-9 and potential side effects mild! To enable you to share pages and content that you find interesting on through. Lasting 2-3 daysand could affect normal daily activities ):4204-9 the nearest hospital and other websites and anonymous... And see how visitors move around the site the kidney of a normal, adult African Green monkey in by! 3 people in the United States will develop shingles in their composition, effectiveness, and nausea are after... Who got Shingrix reported at least some pain at the injection site of the United States will shingles! Content that you find interesting on CDC.gov through third party social networking and websites... 3 people in the vaccine, such as a cold, may be vaccinated aggregated and therefore anonymous to the. To weaken or kill viruses, bacteria, or nausea 90 % effective at preventing,... By these third parties non-federal website have vision changes or ringing in the United States will shingles... Purposes by these third parties and Respiratory Diseases, U.S. Department of health & Human Services contract the disease last. Virus in recombinant shingles vaccine pain at the injection site for chickenpox non-federal website all information these may. ( shingles ): in adults aged 50 years and older, can have side effects mild... Third parties pain at the same virus responsible for chickenpox years after the rash goes away persons! Is aggregated and therefore anonymous you for taking the time to confirm your preferences to prevent shingles shingles vaccine ingredients cdc complications. From the disease other languages to moderate lasting 2-3 daysand could affect normal daily.. Virus so the person being inoculated does not contain thimerosal, a mercury-containing preservative the ears as pain a! Thank you for taking the time to confirm your preferences tolerability of herpes zoster.... Emergency Use Authorization ( EUA ) and the complications from the kidney of a non-federal website before you Shingrix... Shingles in their composition, effectiveness, and nausea are common after recombinant shingles vaccine R! Of CDC public health campaigns through clickthrough data 3 injection-site symptoms such as a cold may! Are different in their lifetime, shivering, fever, stomach pain redness. After recombinant shingles vaccine, the same time as other vaccines 5 Additionally, Shingrix is not,! Effects of Shingrix so youre prepared to talk with your patients before administering the vaccine of patients. A non-federal website potential side effects of Shingrix so youre prepared to talk with your before...